000			01864i0n a2200301 4500
001			u7478
003			SIRSI
005			20251211094535.0
008			|a250904s2023 enka r 001|0 eng d
020			_a9780323916172
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ _dclrauoh
082			_2612.67
100			_aFang, Evandro Fei, _eauthor.
245	1	0	_aMolecular, cellular, and metabolic fundamentals of human aging / _cEvandro Fei Fang, Linda Hildegard Bergersen, Brian C. Gilmour.
264			_c©2023
300			_a246 pages : _billustrations.
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
520			_aMolecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, mitochondrial dysfunction, the impact of decreased ability of autophagosomes and autophagosomes, cellular senescence, changes to communication molecules, and the impact of stem cell exhaustion. The book also considers the impact of aging within the immune system, the relationship between aging and diseases such as cancers and neurodegenerative conditions, and provides an overview on the dialogue surrounding the topic of aging beyond basic biology.
650			_aAging _xMolecular aspects.
650			_aEnvejecimiento _xAspectos moleculares. _2localuoh
650			_aAging _xPhysiological aspects.
650			_aEnvejecimiento _xAspectos psicológicos. _2localuoh
700			_aGilmour, Brian C., _eauthor.
700			_aBergersen, Linda Hildegard, _eauthor.
942			_2ddc _cBOOK
999			_c6494 _d6494